
Covering the spectrum of

iVIZIA lubricant eye drops offer an advanced formulation and innovative bottle design in an over-the-counter (OTC) solution to provide relief for your patients who suffer from dry eyes.

Advantages of iVIZIA Lubricant Eye Drops

*To limit blurriness when using contact lenses, remove contacts, apply drops, then insert contacts.
†Source: Rx market data, Dec. 2022 - S01K without cyclosporine
Tackle the vicious circle of dry eye

The ingredients in iVIZIA target every entry point of the vicious dry eye circle with 4 actions that enable cells to maintain viability while strengthening the tear film and improving its stability:
- Osmoregulation—allows the balance of the osmotic pressure on both sides of the cell membrane and thus limits the movement of water4,12
- Hypotonic formulation designed to combat hyperosmolarity in the tear film
- Prevents water leakage from cytoplasm (osmoprotection)
- Stabilizes lipid bilayers13
- Protects proteins13
- Prevents denaturation/degeneration of proteins13
- Induces autophagy (recycling of cell materials) to maintain cell homeostasis and reduce apoptosis (cell death)1,4
Help your patients see eye care differently


iVIZIA Lubricant Eye Drops—a preservative-free formulation with the active ingredient povidone
- Active ingredient enhanced by trehalose and hyaluronic acid (HA)
- Trehalose provides bioprotection, osmoprotection, and rehydration1-4
- HA and povidone deliver lubrication with long-lasting relief 5,6
- Increased tear film thickness for up to 240 minutes9
- Packaged in the proprietary ABAK™ bottle—a multi-dose bottle capable of delivering calibrated eye drops
- Suitable for all dry eye sufferers, including contact lens wearers*

iVIZIA Eyelid Cleansing Wipes—convenient daily cleansing for sensitive eyelids
- No preservatives, parabens, soaps, or perfumes
- Micellar formula gently breaks up and lifts lid oils and makeup
- Ingredients include botanicals and zinc
- No rinsing necessary after use
- Clinically shown to reduce eyelid discomfort over time23
iVIZIA Micellar Eyelid Cleanser—economical daily cleansing for eyelids
- Liquid formulation with no BAK preservatives, parabens, soaps, or perfumes
- Suitable for daily hygiene of eyelids, particularly at the base of the eyelashes
- Micellar formula gently breaks up and lifts lid oils and makeup
- No rinsing necessary after use
iVIZIA Eyelid Cleansing Gel—economical daily cleansing for sensitive eyelids
- Preservative free, using proprietary Steri-Free Technology to protect gel from bacteria contamination after opening
- Only 5 ingredients—each providing efficacy and safety to gently remove oils and makeup
- Accurate and regular doses dispensed via the Mega Airless Pump
- No rinsing necessary after use
- Clinically shown to be a gentle and effective formula24
The iVIZIA Story

* Source: Rx market data, Dec. 2022 - S01K without cyclosporine

Open your patients’ eyes to innovative eye care with iVIZIA

References: 1. Chen W, Zhang X, Liu M, et al. Trehalose protects against ocular surface disorders in experimental murine dry eye through suppression of apoptosis. Exp Eye Res. 2009;89(3):311-318. 2. Aragona P, Colosi P, Rania L, et al. Protective effects of trehalose on the corneal epithelial cells. ScientificWorldJournal. 2014;2014:717835. 3. Chiambaretta F, Doan S, Labetoulle M, et al. A randomized, controlled study of the efficacy and safety of a new eyedrop formulation for moderate to severe dry eye syndrome. Eur J Ophthalmol. 2017;27(1):1-9. 4. Liu Z, Chen D, Chen X, et al. Trehalose induces autophagy against inflammation by activating TFEB signaling pathway in human corneal epithelial cells exposed to hyperosmotic stress. Invest Ophthalmol Vis Sci. 2020;61(10):26. 5. US FDA Department of Health and Human Services. Ophthalmic drug products for over-the-counter human use. Updated October 21, 2021. Accessed January 19, 2022. https://www.accessdata.fda. gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=349. 6. Jones L, Downie LE, Korb D, et al. TFOS DEWS II management and therapy report. Ocul Surf. 2017;15(3):575-628. 7. Pisárčik M, Bakoš D, Čeppan M. Non-Newtonian properties of hyaluronic acid aqueous solution. Colloids Surf A Physicochem Eng Asp. 1995;97(3):197-202. 8. Rah MJ. A review of hyaluronan and its ophthalmic applications. Optometry. 2011;82(1):38-43. 9. Schmidl D, Schmetterer L, Witkowska KJ, et al. Tear film thickness after treatment with artificial tears in patients with moderate dry eye disease. Cornea. 2015;34(4):421-6. 10. Fariselli C, Giannaccare G, Fresina M, Versura P. Trehalose/hyaluronate eyedrop effects on ocular surface inflammatory markers and mucin expression in dry eye patients. Clin Ophthalmol. 2018;12:1293-1300. 11. Gabisson P, Briat B, Le Foll J, et al. Handiness and acceptability of the new ABAK bottle in chronically treated patients. A cross-sectional, retrospective and multicentre study. Ann Pharm Fr. 2010;69(1):22-29. 12. Hovakimyan M, Ramoth T, Löbler M, et al. Evaluation of protective effects of trehalose on desiccation of epithelial cells in three dimensional reconstructed human corneal epithelium. Curr Eye Res. 2012;37(11):982-989. 13. Luyckx J, Baudouin C. Trehalose: an intriguing disaccharide with potential for medical application in ophthalmology. Clin Ophthalmol. 2011;5:577-581. 14. Baudouin C, Messmer EM, Aragona P, et al. Revisiting the vicious circle of dry eye disease: a focus on the pathophysiology of meibomian gland dysfunction. Br J Ophthalmol. 2016;100(3):300-306. 15. Mochizuki H, Yamada M, Hato S, Nishida T. Fluorophotometric measurement of the precorneal residence time of topically applied hyaluronic acid. Br J Ophthalmol. 2008;92(1):108-111. 18. You IC, Li Y, Jin R, Ahn M, Choi W, Yoon KC. Comparison of 0.1%, 0.18%, and 0.3% Hyaluronic Acid Eye Drops in the Treatment of Experimental Dry Eye. J Ocul Pharmacol Ther. 2018;34(8):557-564. 19. Kojima T, Nagata T, Kudo H, et al. The Effects of High Molecular Weight Hyaluronic Acid Eye Drop Application in Environmental Dry Eye Stress Model Mice. Int J Mol Sci. 2020;21(10):3516. Published 2020 May 15. 20. Ehrenberg M, Zolotariov E, Loeb E, Poliansky V, Levy A. Combining Sodium Hyaluronate and Polyvinylpyrrolidone Therapies for the Rabbit Cornea: A New Approach to Relief of the Human Dry Eye Syndrome. Curr Eye Res. 2015;40(9):913-922. 21. Otto S, Roth HW. Wirksamkeit und Verträglichkeit eines Polyvidon-Präparates bei Behandlung von Benetzungsstörungen [Effectiveness and tolerance of a polyvidon substance in treatment of dry eye syndromes]. Klin Monbl Augenheilkd. 1996;209(6):362-367. 22. Baudouin C, Labbé A, Liang H, Pauly A, Brignole-Baudouin F. Preservatives in eyedrops: the good, the bad and the ugly. Prog Retin Eye Res. 2010;29(4):312-334. 23. Guillon M, Maissa C, Wong S. Symptomatic relief associated with eyelid hygiene in anterior blepharitis and MGD. Eye Contact Lens. 2012;38(5):306-312. 24. Serge Doan. Clinical Ophthalmology. January 10, 2012. Bichat Hospital and Foundation. Paris, France. 25. Data on File. Laboratoires Théa.